OUR RESEARCH & EVIDENCE
Trust the science
Clinically validated in published, peer-reviewed research with Karolinska Institutet. Used by thousands of families for years — significantly outperforming traditional treatment.
Key findings
Clinically validated in published, peer-reviewed research with Karolinska Institutet
-0.30
BMI SDS reduction / year
Double the effect of traditional treatment with Evira.
3 yrs
Sustained outcomes
Treatment effects maintained after three years. KI follow-up, 2025.
78%
Family satisfaction
vs 11% in traditional care. Especially effective with adolescents.
70%
More likely remission
Reach below obesity threshold.
−45%
Fewer cancelled visits
40% vs 85% cancelling over 6 months.
0
Eating disorders
No ED diagnoses during or after treatment due to Evira.
Results exceed USPSTF benchmarks — which require ≥26 hours of professional support per year — with significantly lower resource requirements.
ONE-YEAR PRAGMATIC TRIAL
Significantly greater relative weight loss
In our one-year study with researchers from Karolinska Institutet, the first 107 patients at Martina Children's Hospital Centre for Weight Health used Evira's platform and treatment method for one year. A matched control group of 321 patients was randomly selected from the national quality registry BORIS, receiving traditional treatment during the same period.
The intervention group using Evira achieved a relative weight reduction of 0.30 WHO BMI SDS units, compared to 0.15 in the control group. A particularly strong effect was seen in adolescents — a treatment group that has been historically very difficult to reach with traditional treatment.
Treatment with Evira is also less resource-intensive than the treatments underlying USPSTF results, which require at least 26 hours of professional support per year.
Hagman E, Johansson L, et al. International Journal of Obesity, 2022.
THREE-YEAR FOLLOW-UP
Long-term effects maintained — no weight regain
This follow-up study from Karolinska Institutet, based on the same cohort of 428 children and adolescents (ages 4–17), shows that the relative weight reduction achieved with Evira after one year was maintained for up to three years.
Key findings:
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Weight loss maintained
Patients using Evira lost twice as much relative weight as the control group at one year — and maintained it for three years.
🤝
Higher treatment adherence
Significantly fewer patients dropped out compared to standard treatment.
🎯
70% more likely to achieve remission
Reaching a BMI below the obesity threshold, compared to standard treatment.
🛡️
No eating disorders
No patient using Evira developed an eating disorder diagnosis during treatment or in the year that followed. Three patients showed signs of disordered eating — all already in specialist psychiatric care.
Hagman E, Lindberg L, et al. International Journal of Obesity, 2025.
FEASABILITY STUDY
Early validation across three clinics
During Evira's initial phase, the platform was tested in a feasibility study at three clinics over six months. The study showed good treatment effect compared to traditional treatment. Almost all families using Evira reported that it helped them reach their treatment goals and that it was easier to get in touch with clinicians. Families using Evira were significantly more satisfied with treatment results compared to the control group.
Johansson L, Hagman E, Danielsson P. BMC Pediatrics, 2020.
From prototype to scalable treatment tool
A process evaluation of the original RCT (2018–2019) identified implementation challenges and insights from an early-stage digital prototype. These learnings have been central to the user-centred development that shaped Evira into the treatment tool it is today — more intuitive, technologically mature, and offering real-time support with structured training for care providers.
Linnea Johansson, PhD, researched mobile health interventions with Evira as the main focus in her doctoral thesis at Karolinska Institutet. She concludes that digital health interventions combined with clinical visits provide a better treatment effect than behavioural treatment alone — and emphasises the importance of technical maturity and structured training for clinical staff.
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Process evaluation
Hedin L, Hagströmer M, et al. Sage Open Pediatrics, 2025.
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Doctoral thesis
Johansson L. Mobile health interventions and cardiorespiratory fitness in pediatric obesity. Karolinska Institutet, 2022.
Real-world implementation
Beyond clinical studies, Evira is deployed across 20+ CEW clinics in England (NHS England contract since 2023), 20+ paediatric clinics in Sweden, and adult weight management supporting 3,000+ adults.
Ongoing research
In addition to published studies, several research projects are underway.
EurEvira — international multicentre study
Evaluating Evira alongside local childhood obesity treatment in several European countries.
ClinicalTrials.gov →
Non-inferiority study, Abu Dhabi
60 patients at Sheikh Shakhbout Medical City followed for 26 weeks. Comparing results with published Martina data in a different cultural context. Study complete — article under review.
Evira + anti-obesity medication (RCT)
Randomised controlled trial at multiple Swedish clinics evaluating whether combining Evira with pharmacological treatment improves outcomes vs medication alone. Recruiting clinics.
ClinicalTrials.gov →
Eating disorders & disordered eating
Multiple ongoing studies examining whether Evira affects prevalence of ED/DEB during and after treatment. Retrospective chart review of 315 patients.
Published research
Process evaluation of an RCT with a mobile health intervention for children with obesity
Hedin L, Hagströmer M, Marcus C, Danielsson P. Sage Open Pediatrics, 2025.
Long-term results of a digital treatment tool: a 3-year pragmatic clinical trial
Hagman E, Lindberg L, Putri RR, Drangel A, Marcus C, Danielsson P. International Journal of Obesity, 2025.
Effect of an interactive mobile health support system: a one-year pragmatic clinical trial
Hagman E, Johansson L, Kollin C, Marcus E, Drangel A, Marcus L, Marcus C, Danielsson P.
Mobile health interventions and cardiorespiratory fitness in pediatric obesity
Johansson L. Doctoral thesis, Karolinska Institutet, 2022. ISBN: 978-91-8016-515-0
A novel interactive mobile health support system: a randomised controlled feasibility trial
Johansson L, Hagman E, Danielsson P. BMC Pediatrics, 2020.
Further publications are in progress — one article under review (Abu Dhabi non-inferiority study) and additional manuscripts in preparation.